Center «Photonics and photochemistry of molecules»

Head of the Center: Sergey Terekhov , PhD

Directions of research and development:

Photonics of native and model biomolecular systems in order to develop new techniques and compounds that are promising for use in biomedicine and biotechnology.

Photonics of supramolecular ensembles based on natural and synthetic compounds in order to establish the mechanism and dynamics of energy and electron transfer, structural relaxation processes with subsequent possible use of molecular electronics and opto-electronic devices in nanotechnology.

Photonics of supramolecular heterostructures with the participation of semiconductor nanocrystals and organic chromophores designed to create new photostable composite sensor materials and high-speed opto-electronic nanoscale elements.

Laser kinetic spectroscopy of relaxation processes of the interaction of molecular oxygen with respiratory proteins by hemoglobin, myoglobin and artificial blood substitutes.

Quantum-chemical calculations of the structure, spectroscopic and physicochemical properties of molecules in order to establish the mechanisms of photochemical processes in native and artificial systems.

Molecular oxygen photonics: photosensitized generation of its active forms and photodynamic effect on biological objects, including malignant tumors. Search for new effective photosensitizers of singlet oxygen.

Development of the physical fundamentals of new methods for creating remote optical sensors.

High-resolution spectroscopy to study the properties of metal-organic compounds with selective laser excitation and low temperatures.

Development and optimization of new highly efficient substrates for giant Raman scattering based on metallized porous silicon and anodic alumina for use as active components of sensors for biomedical and analytical purposes, in particular for non-invasive medical diagnostics of biological fluids and forensic examination.

Development and research of photophysical properties of new hybrid materials based on nanostructured porous silicon complexes with natural and synthetic biomolecules.

Main publications:
K.V. Girel, A.Yu. Panarin, H.V. Bandarenka, G. Isic, V.P. Bondarenko and S N Terekhov. Plasmonic silvered nanostructures on macroporous silicon decorated with graphene oxide for SERS-spectroscopy. Nanotechnology. 2018, V. 29, 395708 (12pp).

H.V. Bandarenka, K. V. Girel, S. A. Zavatski, A. Panarin, S. N. Terekhov. Progress in the Development of SERS-Active Substrates Based on Metal-Coated Porous Silicon. Materials. 2018, V. 11(5), 852-871.

I.V. Shelaev, F.E. Gostev, T.V. Vygodina, S.V. Lepeshkevich, B.M. Dzhagarov. Femtosecond absorption spectroscopy of cytochrome c oxidase: excited electronic states and relaxation processes in heme a and heme a3 centers. High Energy Chemistry. 2018, V. 52 (1), P. 45-51.

I.P. Pozdnyakov, P.S. Sherin, V.A. Salomatova, M.V. Parkhats, V.P. Grivina, B.M. Dzhagarov. Photooxidation of herbicide Amitrole in the presence of fulvic acid. Environ. Sci. Pollut. Res. 2018, V. 25, P. 20320 — 20327.

N.V. Ivashin, E.E. Shchupak Quantum-Chemical Simulation of the Solvent Effect on Spontaneous Emission of Singlet Oxygen. Optics and Spectroscopy. 2018, V. 124 (1), Р.32–42.
Gorski, V. Knyukshto, E. Zenkevich, A. Starukhin, T. Lyubimova. Temperature dependent steric hindrance effects in triplet state relaxation of meso-phenyl-substituted Pd-octaethylporphyrins. Journal of Photochemistry and Photobiology A: Chemistry. 2018, V. 354, P. 101-111.

Gorski, A. Starukhin, S. Stavrov, S. Gawinkowski, J. Waluk. Resonance Raman spectroscopy study of protonated porphyrin. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2017, V. 173, P. 350–355.

I.V. Aksenova, R.T. Kuznetsova, I. P. Pozdnyakov, V. F. Plyusnin, M.B. Berezin, N. A. Bumagina, E. S. Jarnikova, M. V. Parkhats, B. M. Dzhagarov. Spectral-kinetic properties and efficiency of singlet oxygen generation by some dipyrromethenes. J. Photochem. Photobiol. A: Chem. 2017, V. 344, P. 206 — 211.

A.Yu. Panarin, А.V. Abakshonok, А.N. Eryomin, S.N. Terekhov. Spectral manifestation of surface plasmon resonance of silver nanoparticles upon interaction with water-soluble metalloporphyrins. Optics and Spectroscopy. 2017, V. 122(6), 896-900.

S.V. Lepeshkevich, S.N. Gilevich, M.V. Parkhats, B.M. Dzhagarov. Molecular oxygen migration through the xenon docking sites of human hemoglobin in the R-state. Biochim. Biophys. Acta. 2016, V. 1864, № 9, P. 1110-1121.

V. Bandarenka, K. V. Girel, V. P. Bondarenko, I. A. Khodasevich, A. Yu. Panarin, S. N. Terekhov. Formation Regularities of Plasmonic Silver Nanostructures on Porous Silicon for Effective Surface-Enhanced Raman Scattering. Nanoscale Research Letters. 2016, V. 11, 262.

N. Terekhov, S. M. Kachan, A.Yu. Panarin, P. Mojzes. Surface-enhanced Raman scattering on silvered porous alumina templates: role of multipolar surface plasmon resonant modes. Phys. Chem. Chem. Phys. 2015. V.17, P. 31780 – 31789.

S. Stasheuski, V. A. Galievsky, A. P. Stupak, B. M. Dzhagarov, M. J. Choi, B. H. Chung, J. Y. Jeong. Photophysical Properties and Singlet Oxygen Generation Efficiencies of Water-Soluble Fullerene Nanoparticles. Photochemistry and Photobiology. 2014, V. 90, P. 997-1003.

S.V. Lepeshkevich, M.V. Parkhats, A.S. Stasheuski, V.V. Britikov, E.S. Jarnikova, S.A. Usanov, B.M. Dzhagarov. Photosensitized Singlet Oxygen Luminescence from the Protein Matrix of Zn-Substituted Myoglobin. J. Phys. Chem. A. 2014, V. 118, № 10, P. 1864-1878.

B.M. Dzhagarov, E.S. Jarnikova, M.V. Parkhats, A.S. Stasheuski. Dependence of the spontaneous emission of singlet oxygen on the refractive index and molecular polarizability of the surrounding dielectric media. Оптика и спектроскопия. 2014, Т. 116 (6), С. 1003 — 1008.

Yu. Panarin, I. A. Khodasevich, O. L.Gladkova, S. N. Terekhov, Determination of antimony by surface-enhanced Raman spectroscopy. Applied Spectroscopy. 2014, V. 68 (3), P. 297-306.
S.V. Lepeshkevich, A.S. Stasheuski, M.V. Parkhats, V.A. Galievsky, B.M. Dzhagarov. Does photodissociation of molecular oxygen from myoglobin and hemoglobin yield singlet oxygen? J. Photochem. Photobiol. B: Biol. 2013, V. 120, P. 130-141.

Mogilevtsev D., Maloshtan A., Lepeshkevich S.V., Dzhagarov B.M. Spontaneous emission of singlet oxygen near dielectric nano-objects and radiative diagnostics of bio-objects. J. Fluoresc. 2012, V. 22, P.1415 – 1419.

S.V. Lepeshkevich, S.A. Biziuk, A.M. Lemeza, B.M. Dzhagarov. The kinetics of molecular oxygen migration in the isolated α chains of human hemoglobin as revealed by molecular dynamics simulations and laser kinetic spectroscopy. Biochim. Biophys. Acta. 2011, V. 1814, № 10, P. 1279-1288.

S.N. Terekhov, P. Mojzes, S.M. Kachan, N.I. Mukhurov, S.P. Zhvavyi, A.Yu. Panarin, I.A. Khodasevich, V.A. Orlovich, A. Thorel, F. Grillon and P.-Y. Turpin. A comparative study of surface-enhanced Raman scattering from silver-coated anodic aluminium oxide and porous silicon. J. Raman Spectrosc. 2011, V. 42, P. 12-20.

S.V. Lepeshkevich, M.V. Parkhats, I.I. Stepuro, B.M. Dzhagarov. Molecular oxygen binding with α and β subunits within the R quaternary state of human hemoglobin in solutions and porous sol-gel matrices. Biochim. Biophys. Acta. 2009, V. 1794, № 12, P. 1823-1830.

H.A. Isakau, M.V. Parkhats, V.N. Knyukshto, B.M. Dzhagarov, E.P. Petrov, P.T. Petrov. Toward understanding the high PDT efficacy of chlorin e6 — polyvinylpyrrolidone formulations: Photophysical and molecular aspects of photosensitizer — polymer interaction in vitro. J. Photochem. Photobiol. B: Biol. 2008, V. 92, P. 165-174.